our difference

BioAdvance CBD™ a water-based CBD with 30x the penetration of regular CBD oil.

Most CBD infused skincare products today are oil-based.

The problem with oil based products is that CBD’s topical bioavailability is very low – very little CBD makes it past the very  topmost layer of skin to where it can actually do some good.

We knew there was a better way.

We developed BioAdvance CBD™ a water-based CBD with 30x the penetration of regular CBD oil.


    BioAdvanceCBD™ absorbs up to 30x more than regular CBD. In order to experience the amazing benefits of CBD, it needs to penetrate the skin to reach our endocannabinoid receptors. Regular CBD is oil based and shows very poor absorption yet is used by the entire industry.

    We at American Vanity were not satisfied with this solution and searched for a better way.

    Our search led us to water dispersible CBD technology, which we used to developed BioAdvance CBD™ using certified organic, US-grown CBD Isoalte.

  • anti-inflammatory

    CBD has demonstrated powerful anti-inflammatory effects in numerous early studies. In fact, CBD has been shown to help with such inflammation-related skin conditions as psoriasis, dermatitis, acne, eczema, arthritis related pain and nerve damage, and rosacea (1)


    CBD has been shown to provide significant improvement in arthritis related pain and inflammation. Further, CBD’s poor oral bio-availability means topical products offer the ideal solution for localized pain (2).

  • Anti-acne

    Acne vulgaris is caused by sebum overproduction, unwanted sebocyte proliferation, and inflammation. If this looks a lot like a list of CBD’s benefits, it is! In fact, early research is showing CBD is highly effective in treating acne and reducing break-outs and redness (3). The greatly increased penetration of BioAdance CBD make cannabidiol the ideal solution for acne without resorting to harsh and unsafe chemical products.

  • Anti-microbial properties

    Researchers have recently demonstrated that cannabidiol is active against bacteria including such as drug-resistant Staphylococcus (4). In addition to treating serious infections, CBD’s anti-bacterial properties tie in to its effects on acne and other common skin conditions.

  • powerful anti-oxidant

    CBD has also been shown to act as a powerful anti-oxidant (5). CBD is rich in fatty acids (particularly omega 3) and vitamins A, D, and E. In fact the US Federal Government registered a patent on the antioxidant and neuroprotective effects of cannabinoids in 2003 while strictly deeming the cannabis plant illegal!


    (1) https://echoconnection.org/cannabinoids-soothe-psoriasis-eczema-skin-diseases/
    (2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/
    (3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151231/
    (4) https://www.genengnews.com/news/cbd-as-a-next-gen-antibiotic/
    (5) https://pubs.rsc.org/en/content/articlelanding/2019/an/c9an00890j#!divAbstract

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